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| Gonçalves,Gisele Mara Silva; Campos,Patrícia Maria Berardo Gonçalves Maia. |
| O trabalho aborda a aplicação dos métodos de biofísica no estudo de eficácia de produtos dermocosméticos. A qualidade de um produto cosmético engloba a segurança de seu uso, a estabilidade da formulação, o aspecto, o sensorial e a sua eficácia. As técnicas de biofísica têm sido amplamente empregadas na avaliação do efeito de formulações dermocosméticas, principalmente devido ao fato de possibilitarem a avaliação de produtos em suas reais condições de uso, ou seja, na pele humana. A comprovação dos efeitos de produtos cosméticos e a elucidação de seu mecanismo de ação por meio de protocolos experimentais devidamente elaborados, que utilizem as técnicas de biofísica da pele, dentre outras, tornam-se de fundamental importância e, assim, a serem amplamente... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Produtos dermocosméticos/controle de qualidade; Pele/biofísica; Pele/estudo; Biofísica/técnicas; Biofísica/aplicação em cosmetologia; Cosméticos/eficácia; Dermocosmetic products/quality control; Skin/biophysics; Skin/study; Biophysics/techniques; Biophysics/cosmetologic application; Cosmetics/effectiveness. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000100002 |
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| Barros,Pedro Paulo; Silva,Gustavo Henrique da; Gonçalves,Gisele Mara Silva; Oliveira,Jessica Cristiane; Pagnan,Livia Gonçalves; Arco-e-Flexa,Luiza. |
| ABSTRACT Quercetin has potent antioxidant action and a hepatoprotective role. The aim of this study was to evaluate the hepatoprotective action of quercetin pretreatment in paracetamol-induced liver damage (PILD) and structural injury resulting from partial hepatectomy (PH). In the first model, Wistar rats received oral quercetin (50mg/kg/day) during 8 days. On the 8th day, 3g/kg paracetamol were added. In the second model, the same quercetin dose was given during 7 days and rats were submitted to PH on the 8th day. Blood samples were obtained for determination of enzyme levels. Liver, heart, kidney and lung tissue were also collected for assessment of quercetin biodistribution and/or histological analyses. The results obtained after PILD were more... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Quercetin; Paracetamol; Partial hepatectomy; ALT; AST. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100302 |
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| Gonçalves,Gisele Mara Silva; Srebernich,Silvana Mariana; Vercelino,Bartira Guiçardi; Zampieri,Bruna Melli. |
| The aim of the present study was to evaluate the sensory assessments of identical cosmetic formulations with and without fragrance to investigate not only the acceptance but also how different fragrances affected their attributes, such as skin feel, tackiness and spreadability. Three gel and three cream formulations with and without two types of fragrance, fennel and sweet flowers, were assessed for various attributes. The presence and type of fragrance used affected the testers' perception of some attributes, showing that the influence of this component should not be disregarded. Apparently, a consumer's reaction to a cosmetic product is not only based on its efficacy but also on how its attributes are perceived, such as appearance, skin feel and smell. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cosmetics; Development; Fragrance; Olfactory memory; Sensory. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200005 |
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| Gonçalves,Gisele Mara Silva; Silva,Gustavo Henrique da; Barros,Pedro Paulo; Srebernich,Silvana Mariana; Shiraishi,Cecilia Toyoko Cavalcanti; Camargos,Victória Rodrigues de; Lasca,Thais Barbiero. |
| Curcuma longais a ginger family aromatic herb (Zingiberaceae) whose rhizomes contain curcuminoid pigments, including curcumin, a compound known for its anti-inflammatory effects. The objective of this study was to obtain curcuminoid-rich extracts, develop topical formulations thereof, and assess the stability and skin permeation of these formulations. Curcuma longa extracts were obtained and used to develop formulations. Skin permeation studies were conducted in a modified Franz diffusion cell system, and skin retention of curcuminoid pigments was quantified in pig ear membrane. Prepared urea-containing gel-cream formulations were unstable, whereas all others had satisfactory stability and pseudoplastic rheological behavior. The amount of curcuminoid... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Curcuma longa/pharmacognosy; Curcumin/use/topical anti-inflammatory; Cosmetics/use of natural products; Curcuminoid pigments; Skin penetration; Natural products/use in cosmetics. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400885 |
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